和歌山県立医科大学 薬学部
薬剤学研究室
Publications
2023
Fukuta, T.*, Ikeda-Imafuku, M., Kodama, S., Kuse, J., Matsui, K., Iwao, Y.* (2023). One-Step Pharmaceutical Preparation of PEG-Modified Exosomes Encapsulating Anti-Cancer Drugs by a High-Pressure Homogenization Technique. Pharmaceuticals, 16(1), 108.(*Corresponding author)
Gao, Y, Ikeda-Imafuku, M., Zhao, Z., Joshi, M., Mitragotri, S. (2023). A polymer-based systemic hemostat for managing uncontrolled bleeding. Bioengineering & Translational Medicine, e10516.
Fukuta,T., Ikeda-Imafuku, M., Iwao,Y.(2023). Development of Edaravone Ionic Liquids and Their Application for the Treatment of Cerebral Ischemia/Reperfusion Injury . Molecular Pharmaceutics,mp-2023-001038.
Sakakibara, O.; Shimoda, M.; Yamamoto, G.; Higashi, Y.; Ikeda-Imafuku, M.; Ishima, Y.; Kawahara, M.; Tanaka, K.-i. Effectiveness of Albumin-Fused Thioredoxin against 6-Hydroxydopamine-Induced Neurotoxicity In Vitro. Int. J. Molecular Sciences 2023, 24, 9758.
Tatsuya Fukuta,*,a Akina Nishikawa,b Ami Hiramachi,c Sachika Yamashita,c and Kentaro Kogure.(2023).Development of Functional Chimeric Nanoparticles by Membrane Fusion of Small Extracellular Vesicles and Drug-Encapsulated Liposomes.Biological and Pharmaceutical Bulletin, 46, 1098–1104 (2023)
Kengo Yasuda, Hitoshi Maeda, Ryo Kinoshita, Yuki Minayoshi, Yuki Mizuta, Yuka Nakamura, Shuhei Imoto, Koji Nishi, Keishi Yamasaki, Mina Sakuragi, Teruya Nakamura, Mayumi Ikeda-Imafuku, Yasunori Iwao, Yu Ishima, Tatsuhiro Ishida, Yasuko Iwakiri, Masaki Otagiri, Hiroshi Watanabe and Toru Maruyama(2023).Encapsulation of an Antioxidant in Redox-Sensitive Self-Assembled Albumin Nanoparticles for the Treatment of Hepatitis.ACS Nano,3c02877
2022
Khatun, A., Hasan, M., Abd El-Emam, M. M., Fukuta, T., Mimura, M., Tashima, R., ... & Kogure, K. (2022). Effective Anticancer Therapy by Combination of Nanoparticles Encapsulating Chemotherapeutic Agents and Weak Electric Current. Biological and Pharmaceutical Bulletin, 45(2), 194-199.
Fukuta, T.*, Oku, N., & Kogure, K. (2022). Application and Utility of Liposomal Neuroprotective Agents and Biomimetic Nanoparticles for the Treatment of Ischemic Stroke. Pharmaceutics, 14(2), 361. (*Corresponding author)

Hasan, M.#, Fukuta, T.#, Inoue, S., Mori, H., Kagawa, M., & Kogure, K. (2022). Iontophoresis-mediated direct delivery of nucleic acid therapeutics, without use of carriers, to internal organs via non-blood circulatory pathways. Journal of Controlled Release, 343, 392-399. (#Equal contribution)
Ikeda-Imafuku, M., Wang, L. L. W., Rodrigues, D., Shaha, S., Zhao, Z., & Mitragotri, S. (2022). Strategies to improve the EPR effect: A mechanistic perspective and clinical translation. Journal of Controlled Release, 345, 512-536.

Kimoto, K., Ohashi, K., Iwao, Y., Karashima, M., Yamamoto, K., Fukami, T., Ikeda, Y. (2022). Amorphous characterization of pharmaceutical drug substances enabled by the elastic modulus mapping of atomic force microscope. International Journal of Pharmaceutics, 621, 121784.

Fukuta, T.*, and Kogure, K. (2022). Biomimetic Nanoparticle Drug Delivery Systems to Overcome Biological Barriers for Therapeutic Applications. Chemical and Pharmaceutical Bulletin 70.5, 334-340.

Hirai, D., Tsunematsu, H., Kimura, S. I., Itai, S., Fukami, T., & Iwao, Y. (2022). Theoretical evaluation of supersaturation of amorphous solid dispersion formulations with different drug/polymer combinations using mathematical modeling. International Journal of Pharmaceutics, 625, 122110.
Yoneda, S.#, Fukuta, T.*,#, Ozono, M., Kogure, K. (2022). Enhancement of cerebroprotective effects of lipid nanoparticles encapsulating FK506 on cerebral ischemia/reperfusion injury by particle size regulation. Biochemical and Biophysical Research Communications, 611, 53-59.

Ikeda-Imafuku, M., Gao, Y., Shaha, S., Wang, L. L., Park, K. S., Nakajima, M., Adebowa, O. & Mitragotri, S. (2022). Extracellular matrix degrading enzyme with stroma-targeting peptides enhance the penetration of liposomes into tumors. Journal of Controlled Release, 352, 1093-1103.
