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Publications

2024

Rie Mukai, Hitomi Okuyama, Miku Uchimura, Kozue Sakao, Miyu Matsuhiro, Mayumi Ikeda-Imafuku, Yu Ishima, Miyu Nishikawa, Shinichi Ikushiro, Akihiro Tai.The binding selectivity of quercetin and its structure-related polyphenols to human serum albumin using a fluorescent dye cocktail for multiplex drug-site mapping.Bioorganic Chemistry. https://doi.org/10.1016/j.bioorg.2024.107184

Mayumi Ikeda-Imafuku, Tatsuya Fukuta, Victor Tuan Giam Chuang, Tomohiro Sawa, Toru Maruyama, Masaki Otagiri, Tatsuhiro Ishida  and Yu Ishima.Acute Kidney Injury Caused by Rhabdomyolysis Is Ameliorated by Serum Albumin-Based Supersulfide Donors through Antioxidative Pathways.Pharmaceuticals 2024, 17, 128. https://doi.org/10.3390/ph17010128

血清アルブミンに存在する超硫黄の解析と創薬応用  池田真由美福田達也, 岩尾康範,小田切優樹, 丸山 徹, 石田竜弘, 異島 優. Characterization of Supersulfide in Serum Albumin and Its Therapeutic Application.YAKUGAKU ZASSHI 144, 51–56 (2024)

2023

Tatsuya Fukuta, Mayumi Ikeda-Imafuku, Kodama, S., Kuse, J., Matsui, K., Iwao Yasunori.* (2023). One-Step Pharmaceutical Preparation of PEG-Modified Exosomes Encapsulating Anti-Cancer Drugs by a High-Pressure Homogenization Technique. Pharmaceuticals, 16(1), 108.(*Corresponding author)

Gao, Y, Mayumi Ikeda-Imafuku, Zhao, Z., Joshi, M., Mitragotri, S. (2023). A polymer-based systemic hemostat for managing uncontrolled bleeding. Bioengineering & Translational Medicine, e10516.

Tatsuya FukutaMayumi Ikeda-Imafuku, Iwao,Y.(2023). Development of Edaravone Ionic Liquids and Their Application for the Treatment of Cerebral Ischemia/Reperfusion Injury . Molecular Pharmaceutics,mp-2023-001038.

Sakakibara, O.; Shimoda, M.; Yamamoto, G.; Higashi, Y.; Mayumi Ikeda-Imafuku; Ishima, Y.; Kawahara, M.; Tanaka, K.-i. Effectiveness of Albumin-Fused Thioredoxin against 6-Hydroxydopamine-Induced Neurotoxicity In Vitro. Int. J. Molecular Sciences 2023, 24, 9758. 

Tatsuya Fukuta,*,a Akina Nishikawa,b Ami Hiramachi,c Sachika Yamashita,c and Kentaro Kogure.(2023).Development of Functional Chimeric Nanoparticles by Membrane Fusion of Small Extracellular Vesicles and Drug-Encapsulated Liposomes.Biological and Pharmaceutical Bulletin, 46, 1098–1104 (2023)

Kengo Yasuda, Hitoshi Maeda, Ryo Kinoshita, Yuki Minayoshi, Yuki Mizuta, Yuka Nakamura, Shuhei Imoto, Koji Nishi, Keishi Yamasaki, Mina Sakuragi, Teruya Nakamura, Mayumi Ikeda-Imafuku, Yasunori Iwao, Yu Ishima, Tatsuhiro Ishida, Yasuko Iwakiri, Masaki Otagiri, Hiroshi Watanabe and Toru Maruyama(2023).Encapsulation of an Antioxidant in Redox-Sensitive Self-Assembled Albumin Nanoparticles for the Treatment of Hepatitis.ACS Nano,3c02877

Hiroyuki Koide, Chiaki Kiyokawa, Anna Okishima, Kaito Saito, Keiichi Yoshimatsu, Tatsuya Fukuta, Yu Hoshino, Tomohiro Asai, Yuri Nishimura, Yoshiko Miura, Naoto Oku and Kenneth J. Shea.(2023).Design of an Anti-HMGB1 Synthetic Antibody for In Vivo Ischemic/Reperfusion Injury Therapy.Journal of the American Chemical SocietyVolume 145, Issue 42October 25, 2023Pages22857-23394

Takeru Hirai , Mayumi Ikeda-Imafuku , Nanami Tasaka , Victor Tuan Giam Chung, Ming Xian ,Tatsuhiro Ishida ,  Takaaki Akaike , Yu Ishima.(2023).Human hair keratin responds to oxidative stress via reactive sulfur and  supersulfides.Advances in Redox Research.Volume 10, April 2024, 100091

2022

Khatun, A., Hasan, M., Abd El-Emam, M. M., Tatsuya Fukuta, Mimura, M., Tashima, R., ... & Kogure, K. (2022). Effective Anticancer Therapy by Combination of Nanoparticles Encapsulating Chemotherapeutic Agents and Weak Electric Current. Biological and Pharmaceutical Bulletin, 45(2), 194-199.

Tatsuya Fukuta*, Oku, N., & Kogure, K. (2022). Application and Utility of Liposomal Neuroprotective Agents and Biomimetic Nanoparticles for the Treatment of Ischemic Stroke. Pharmaceutics, 14(2), 361. (*Corresponding author)

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Hasan, M.#, Tatsuya Fukuta, Inoue, S., Mori, H., Kagawa, M., & Kogure, K. (2022). Iontophoresis-mediated direct delivery of nucleic acid therapeutics, without use of carriers, to internal organs via non-blood circulatory pathways. Journal of Controlled Release, 343, 392-399. (#Equal contribution)

Mayumi Ikeda-Imafuku, Wang, L. L. W., Rodrigues, D., Shaha, S., Zhao, Z., & Mitragotri, S. (2022). Strategies to improve the EPR effect: A mechanistic perspective and clinical translation. Journal of Controlled Release, 345, 512-536.

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Kimoto, K., Ohashi, K., Iwao Yasunori., Karashima, M., Yamamoto, K., Fukami, T., Ikeda, Y. (2022). Amorphous characterization of pharmaceutical drug substances enabled by the elastic modulus mapping of atomic force microscope. International Journal of Pharmaceutics, 621, 121784.

Tatsuya Fukuta, and Kogure, K. (2022). Biomimetic Nanoparticle Drug Delivery Systems to Overcome Biological Barriers for Therapeutic Applications. Chemical and Pharmaceutical Bulletin 70.5, 334-340.

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Hirai, D., Tsunematsu, H., Kimura, S. I., Itai, S., Fukami, T., & Iwao, Yasunori. (2022). Theoretical evaluation of supersaturation of amorphous solid dispersion formulations with different drug/polymer combinations using mathematical modeling. International Journal of Pharmaceutics, 625, 122110.

Yoneda, S.#, Tatsuya Fukuta, Ozono, M., Kogure, K. (2022). Enhancement of cerebroprotective effects of lipid nanoparticles encapsulating FK506 on cerebral ischemia/reperfusion injury by particle size regulation. Biochemical and Biophysical Research Communications, 611, 53-59.

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Mayumi Ikeda-Imafuku, Gao, Y., Shaha, S., Wang, L. L., Park, K. S., Nakajima, M., Adebowa, O. & Mitragotri, S. (2022). Extracellular matrix degrading enzyme with stroma-targeting peptides enhance the penetration of liposomes into tumors. Journal of Controlled Release, 352, 1093-1103.

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